Emtricitabin / Rilpivirin / Tenofoviralafenamid (1) – Odefsey®

HIV infection

Characteristics

Start date 15.07.2016 – Marketing authorisation: 21.06.2016
Resolution 05.01.2017
INN Emtricitabin/Rilpivirin/Tenofoviralafenamid
Brand name Odefsey®
Pharm. company Gilead Sciences GmbH
G-BA Procedure ID D-248
ATC code J05AR19 Antivirals for treatment of HIV infections, combinations (J05AR)
DDD 1 U O
Therapeutic area Infectious diseases
Reason for procedure Initial assessment

Studies and Results

  • Clinical trials
    • No results from clinical trials were submitted for the benefit assessment for patient populations a), b), c) and d), and these could therefore not be taken into account.

a) Adults not previously treated with antiretrovirals (treatment-naive)

  • For patient populations a), b), c) and d), an additional benefit over the appropriate comparator therapy is not proven in each case.
  • Consequently, no comparison is possible, either directly or indirectly. It is therefore not possible to draw any conclusions regarding additional benefit, particularly in comparison with the appropriate comparator therapy.

b) adolescents aged 12 years and over who have not previously received antiretroviral therapy (treatment-naive)

  • For patient populations a), b), c) and d), an additional benefit over the appropriate comparator therapy is not proven.
  • Consequently, there is no possibility of comparison, either direct or indirect. It is therefore not possible to draw any conclusions regarding additional benefit, particularly in comparison with the appropriate comparator therapy.

c) Adults who have previously received antiretroviral treatment (treatment-experienced)

  • For patient populations a), b), c) and d), an additional benefit over the appropriate comparator therapy is not proven.
  • Consequently, there is no possibility of comparison, either directly or indirectly. It is therefore not possible to draw any conclusions regarding additional benefit, particularly in comparison with the appropriate comparator therapy.

d) Adolescents aged 12 years and over who have received prior antiretroviral treatment (treatment-experienced)

  • For patient populations a), b), c) and d), an additional benefit over the appropriate comparator therapy is not proven.
  • Consequently, there is no possibility of comparison, either directly or indirectly. It is therefore not possible to draw any conclusions regarding additional benefit, particularly in comparison with the appropriate comparator therapy.

Courtesy translation only, please refer to the German original.

Associated procedures

Emtricitabin / Rilpivirin / Tenofoviralafenamid (1) Odefsey® Gilead Sciences GmbH Infectious diseases HIV infection 56,800–59,300 100% additional benefit not proven


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