15.02.2026
06.08.2026
Imipenem / Cilastatin / Relebactam (3)
Recarbrio®
MSD Sharp & Dohme GmbH
Infectious diseases
Bacterial infections, multiple therapeutic indications, under 18 years of age
519–1,299
100%
additional benefit considered proven
01.02.2026
16.07.2026
Eravacyclin (2)
Xerava®
Paion Pharma GmbH
Infectious diseases
Complicated intra-abdominal infections (cIAI), aged ≥ 12 to < 18 years, weighing ≥ 50 kg
175–440
100%
additional benefit considered proven
15.12.2025
04.06.2026
Nirmatrelvir / Ritonavir (2)
Paxlovid®
Pfizer Pharma GmbH
Infectious diseases
COVID-19, no need for supplemental oxygen, aged ≥ 6 years to < 18 years, weighing ≥ 20 kg
40–230
100%
additional benefit not proven
01.09.2025
19.02.2026
Bulevirtid (4)
Hepcludex®
Gilead Sciences GmbH
Infectious diseases
Hepatitis delta virus (HDV) infection, HDV RNA-positive, aged ≥ 3 years, body weight ≥ 10 kg
400–3,202
100%
additional benefit not proven
Orphan (turnover limit)
15.07.2025
22.01.2026
Remdesivir (5)
Veklury®
Gilead Sciences GmbH
Infectious diseases
COVID-19, no need for supplemental oxygen, ≥ 4 weeks, ≥ 3 kg to <40 kg
23
100%
additional benefit not proven
01.06.2025
20.11.2025
Dalbavancin (3)
Xydalba®
Advanz Pharma Germany GmbH
Infectious diseases
Acute bacterial skin and soft tissue infections (ABSSSI), from birth to < 3 months
16–38
100%
additional benefit considered proven
15.05.2025
06.11.2025
Letermovir (5)
Prevymis®
MSD Sharp & Dohme GmbH
Infectious diseases
CMV infection, prophylaxis following kidney transplantation, < 18 years of age, ≥ 40 kg
13
100%
additional benefit not proven
Orphan (turnover limit)
15.05.2025
06.11.2025
Letermovir (4)
Prevymis®
MSD Sharp & Dohme GmbH
Infectious diseases
CMV reactivation/disease, prophylaxis following stem cell transplantation, < 18 years, ≥ 5 kg
160–240
100%
Hint for
non-quantifiable additional benefit
Orphan (turnover limit)
01.03.2025
21.08.2025
Nirsevimab (3)
Beyfortus®
Sanofi-Aventis Deutschland GmbH
Infectious diseases
Prevention of RSV infections, children during their 1st RSV season, which are not addressed in the therapeutic indication for RSV antibodies
541,000–555,000
100%
Indication of
considerable additional benefit
15.02.2025
07.08.2025
Cabotegravir (2)
Vocabria®
ViiV Healthcare GmbH
Infectious diseases
HIV-1 infection, treatment-experienced adolescents, combination with rilpivirine, 12 to 17 years of age
65
100%
additional benefit not proven
15.02.2025
07.08.2025
Sipavibart (1)
Kavigale®
AstraZeneca GmbH
Infectious diseases
COVID-19, pre-exposure prophylaxis, ≥ 12 years
n.d.
100%
additional benefit not proven
15.11.2024
15.05.2025
Ceftazidim / Avibactam (2)
Zavicefta®
Pfizer Pharma GmbH
Infectious diseases
Bacterial infections, several therapeutic indications, from birth to < 3 years
10–27
100%
additional benefit considered proven
01.11.2024
17.04.2025
Artesunat (1)
Artesunate Amivas®
Amivas Ireland Ltd
Infectious diseases
Severe malaria, from birth
87
100%
non-quantifiable additional benefit
Orphan
01.11.2024
17.04.2025
Meropenem / Vaborbactam (1)
Vaborem®
Berlin-Chemie AG
Infectious diseases
Acterial infections, several therapeutic indications
1,294–1,405
100%
additional benefit considered proven
01.10.2024
20.03.2025
Isavuconazol (3)
Cresemba®
Pfizer Pharma GmbH
Infectious diseases
Mucormycosis, ≥ 1 to ≤ 17 years
8
100%
Hint for
non-quantifiable additional benefit
Orphan
01.10.2024
20.03.2025
Isavuconazol (2)
Cresemba®
Pfizer Pharma GmbH
Infectious diseases
Aspergillosis, ≥ 1 to ≤ 17 years
40–215
100%
Hint for
non-quantifiable additional benefit
Orphan
01.09.2024
20.02.2025
Aztreonam / Avibactam (1)
Emblaveo®
Pfizer Pharma GmbH
Infectious diseases
Bacterial infections, several therapeutic indications
2,600–6,600
100%
additional benefit considered proven
15.08.2024
20.02.2025
Nirsevimab (2)
Beyfortus®
Sanofi-Aventis Deutschland GmbH
Infectious diseases
Secondary prophylaxis of RSV infections, children during their 2nd RSV season, ≥ 24 months of life
9,535
100%
additional benefit not proven
15.06.2024
05.12.2024
Cefepim / Enmetazobactam (1)
Exblifep®
Advanz Pharma Germany GmbH
Infectious diseases
Bacterial infections, several areas of application
1,000–2,600
100%
additional benefit considered proven
01.03.2024
15.08.2024
Nirsevimab (1)
Beyfortus®
Sanofi-Aventis Deutschland GmbH
Infectious diseases
Secondary prophylaxis of RSV infections, children during their 1st RSV season
52,450–66,450
100%
additional benefit not proven
01.02.2024
01.08.2024
Rezafungin (1)
Rezzayo®
Mundipharma
Infectious diseases
Invasive candida infections
31,800–34,600
100%
Hint for
non-quantifiable additional benefit
Orphan
15.12.2023
06.06.2024
Letermovir (3)
Prevymis®
MSD Sharp & Dohme GmbH
Infectious diseases
CMV reactivation/disease, prophylaxis after stem cell transplantation
1,400–1,800
100%
Hint for
non-quantifiable additional benefit
Orphan (turnover limit)
15.12.2023
06.06.2024
Letermovir (2)
Prevymis®
MSD Sharp & Dohme GmbH
Infectious diseases
CMV disease, prophylaxis after kidney transplantation
320
100%
additional benefit not proven
Orphan (turnover limit)
01.08.2023
01.02.2024
Bedaquilin (5)
Sirturo®
Janssen-Cilag GmbH
Infectious diseases
Multidrug-resistant pulmonary tuberculosis
70–100
100%
Hint for
considerable additional benefit
Orphan
01.08.2023
01.02.2024
Dalbavancin (2)
Xydalba®
Advanz Pharma Germany GmbH
Infectious diseases
Acute bacterial skin and soft tissue infections (ABSSSI), ≥ 3 months
190–9,800
100%
additional benefit considered proven
15.05.2023
02.11.2023
Tixagevimab / Cilgavimab (2)
Evusheld®
AstraZeneca GmbH
Infectious diseases
COVID-19, Preexposition prophylaxis, ≥ 12 years
n.d.
100%
additional benefit not proven
01.03.2023
17.08.2023
Dolutegravir / Abacavir / Lamivudin (2)
Triumeq®
ViiV Healthcare GmbH
Infectious diseases
HIV infection, ≥ 14 kg to < 12 years
86
100%
additional benefit not proven
01.01.2023
15.06.2023
Bictegravir / Emtricitabin / Tenofoviralafenamid (2)
Biktarvy®
Gilead Sciences GmbH
Infectious diseases
HIV-Infection, 2 until < 18 years
184
100%
additional benefit not proven
01.12.2022
01.06.2023
Maribavir (1)
Livtencity®
Takeda GmbH
Infectious diseases
Cytomegalovirus infection (CMI), refractory to therapy
90–130
100%
Hint for
minor additional benefit
Orphan
09.02.2023
20.04.2023
Dalbavancin (1)
Xydalba®
Advanz Pharma Germany GmbH
Infectious diseases
Acute bacterial skin and skin structure infections (ABSSSI)
n.d.
n.d.
01.11.2022
20.04.2023
Elvitegravir / Cobicistat / Emtricitabin / Tenofoviralafenamid (3)
Genvoya®
Gilead Sciences GmbH
Infectious diseases
HIV infection, 2 to < 6 years
16
100%
additional benefit not proven
15.10.2022
20.04.2023
Tixagevimab / Cilgavimab (1)
Evusheld®
AstraZeneca GmbH
Infectious diseases
COVID-19, erhöhtes Risiko für schweren Verlauf, ≥ 12 Jahre
n.d.
100%
Hint for
minor additional benefit
15.10.2022
06.04.2023
Remdesivir (4)
Veklury®
Gilead Sciences GmbH
Infectious diseases
COVID-19, no requirement for supplementary oxygen, < 18 years, ≥ 40 kg)
2,600–14,200
100%
additional benefit not proven
15.10.2022
06.04.2023
Remdesivir (3)
Veklury®
Gilead Sciences GmbH
Infectious diseases
COVID-19, need for supplementary oxygen, ≥ 4 weeks - < 12 years
350–1,060
100%
additional benefit not proven
15.08.2022
02.02.2023
Ceftolozan / Tazobactam (7)
Zerbaxa®
MSD SHARP & DOHME GMBH
Infectious diseases
Bacterial infections, multiple indications, < 18 years of age
40
100%
additional benefit considered proven
01.08.2022
19.01.2023
Eravacyclin (1)
Xerava®
PAION Deutschland GmbH
Infectious diseases
Reserve antibiotics: Complicated intra-abdominal infections (cIAI)
2,600–6,600
100%
additional benefit considered proven
01.07.2022
15.12.2022
Nirmatrelvir / Ritonavir (1)
Paxlovid®
Pfizer Pharma GmbH
Infectious diseases
COVID-19, no need for supplementary oxygen, increased risk of severe progression
218,000–1,307,000
100%
Hint for
considerable additional benefit
15.05.2022
03.11.2022
Sotrovimab (1)
Xevudy®
GlaxoSmithKline GmbH & Co. KG
Infectious diseases
COVID-19, ≥ 12 years
n.d.
100%
Hint for
considerable additional benefit
01.05.2022
03.11.2022
Imipenem / Cilastatin / Relebactam (2)
Recarbrio®
MSD Sharp & Dohme GmbH
Infectious diseases
Bacterial infections, multiple indications
2,598–6,600
100%
additional benefit considered proven
01.05.2022
03.11.2022
Ceftolozan / Tazobactam (6)
Zerbaxa®
MSD Sharp & Dohme GmbH
Infectious diseases
Bacterial infections, multiple indications
2,600–6,600
100%
additional benefit considered proven
01.05.2022
03.11.2022
Ceftazidim / Avibactam (1)
Zavicefta®
Pfizer Pharma GmbH
Infectious diseases
Bacterial infections, multiple indications
2,600–6,600
100%
additional benefit considered proven
01.05.2022
20.10.2022
Doravirin / Lamivudin / Tenofovirdisoproxil (2)
Delstrigo®
MSD Sharp & Dohme GmbH
Infectious diseases
HIV infection, 12 to < 18 years
10–20
100%
additional benefit not proven
01.05.2022
20.10.2022
Doravirin (2)
Pifeltro®
MSD Sharp & Dohme GmbH
Infectious diseases
HIV infection, 12 to < 18 years
130–140
100%
additional benefit not proven
15.04.2022
06.10.2022
Casirivimab / Imdevimab (1)
Ronapreve®
Roche Pharma AG
Infectious diseases
Post-exposure prophylaxis of COVID-19 infection, ≥ 12 years
n.d.
100%
Hint for
minor additional benefit
repealed
15.04.2022
06.10.2022
Casirivimab / Imdevimab (2)
Ronapreve®
Roche Pharma AG
Infectious diseases
COVID-19-Infection, ≥ 12 years
n.d.
100%
Hint for
considerable additional benefit
repealed
01.04.2022
15.09.2022
Dolutegravir (4)
Tivicay®
ViiV Healthcare GmbH
Infectious diseases
HIV infection, age 6 to < 18 years
n.d.
n.d.
15.02.2022
04.08.2022
Sofosbuvir / Velpatasvir (3)
Epclusa®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C, ≥ 3 to < 6 years of age
1–12
100%
additional benefit not proven
15.01.2022
07.07.2022
Remdesivir (2)
Veklury®
Gilead Sciences GmbH
Infectious diseases
COVID-19, no need for supplementary oxygen, increased risk of severe progression
218,000–1,307,000
100%
Hint for
minor additional benefit
15.11.2021
05.05.2022
Cefiderocol (2)
Fetcroja®
Shionogi GmbH
Infectious diseases
Infections caused by aerobic gram-negative pathogens
2,600–6,600
100%
additional benefit considered proven
15.11.2021
05.05.2022
Delamanid (1)
Deltyba®
Otsuka Novel Products GmbH
Infectious diseases
Multidrug-resistant pulmonary tuberculosis (TBC), ≥ 10 kg
80–114
100%
Hint for
non-quantifiable additional benefit
Orphan
15.11.2021
05.05.2022
Elbasvir / Grazoprevir (2)
Zepatier®
Merck Sharp & Dohme B.V.
Infectious diseases
Chronic hepatitis C (HCV), 12 to < 18 years
10–17
100%
additional benefit not proven
15.10.2021
07.04.2022
Sofosbuvir / Velpatasvir / Voxilaprevir (2)
Vosevi®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C (HCV), 12 to < 18 years
24–39
100%
additional benefit not proven
23.11.2020
20.01.2022
Imipenem / Cilastatin / Relebactam (1)
Recarbrio®
MSD Sharp & Dohme GmbH
Infectious diseases
Pneumonia, Bacteriemia
n.d.
n.d.
20.08.2020
20.01.2022
Ceftolozan / Tazobactam (5)
Zerbaxa®
MSD Sharp & Dohme GmbH
Infectious diseases
Complicated intra-abdominal infections, acute pyelonephritis, complicated urinary tract infections, hospital-acquired pneumonia (HAP) including ventilator-associated pneumonia (VAP)
n.d.
n.d.
01.07.2021
16.12.2021
Glecaprevir / Pibrentasvir (3)
Maviret®
AbbVie Deutschland GmbH & Co. KG
Infectious diseases
Chronic hepatitis C, 3 to < 12 years
146–238
100%
additional benefit not proven
01.05.2021
21.10.2021
Cabotegravir (1)
Vocabria®
ViiV Healthcare GmbH
Infectious diseases
HIV-1 infection, pre-treated, combination with rilpivirin
59,900
100%
additional benefit not proven
01.05.2021
21.10.2021
Rilpivirin (Rekambys, 1)
Rekambys®
ViiV Healthcare GmbH
Infectious diseases
HIV-1 infection, pre-treated, combination with cabotegravir
59,900
100%
additional benefit not proven
16.07.2020
21.10.2021
Cefiderocol (1)
Fetcroja®
Shionogi GmbH
Infectious diseases
Infections caused by aerobic gram-negative pathogens
n.d.
n.d.
01.04.2021
16.09.2021
Remdesivir (1)
Veklury®
Gilead Sciences GmbH
Infectious diseases
COVID-19, ≥ 12 years, additional oxygen supply
45,000–79,000
34%
Hint for
minor additional benefit
01.04.2021
16.09.2021
Fostemsavir (1)
Rukobia®
ViiV Healthcare GmbH
Infectious diseases
Multidrug-resistant HIV infection
80–240
100%
additional benefit not proven
01.04.2021
16.09.2021
Bedaquilin (4)
Sirturo®
Janssen-Cilag GmbH
Infectious diseases
Multidrug-resistant pulmonary tuberculosis, 5 to 11 years
1
100%
Hint for
non-quantifiable additional benefit
Orphan
15.02.2021
05.08.2021
Baloxavir marboxil (2)
Xofluza®
Roche Pharma AG
Infectious diseases
Influenza prophylaxis, ≥ 12 years
1,909,000–3,965,000
58%
Indication of
considerable additional benefit
15.02.2021
05.08.2021
Baloxavir marboxil (1)
Xofluza®
Roche Pharma AG
Infectious diseases
Influenza, ≥ 12 years
1,871,000–3,303,000
100%
additional benefit not proven
01.02.2021
15.07.2021
Dolutegravir (3)
Tivicay®
ViiV Healthcare GmbH
Infectious diseases
HIV-Infection, children ≥ 4 weeks to < 6 years
29
100%
additional benefit not proven
01.12.2020
20.05.2021
Amikacin (liposomal) (1)
Arikayce liposomal®
Insmed Germany GmbH
Infectious diseases
Mycobacterium avium complex (MAC) lung infections
350–760
100%
Hint for
non-quantifiable additional benefit
Orphan
01.10.2020
01.04.2021
Sofosbuvir / Velpatasvir (2)
Epclusa®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C, ≥ 6 to < 18 years
120
100%
additional benefit not proven
01.09.2020
18.02.2021
Bulevirtid (1)
Hepcludex®
MYR GmbH
Infectious diseases
Chronic hepatitis Delta
0
300–4,800
100%
Hint for
non-quantifiable additional benefit
Orphan
repealed
01.09.2020
18.02.2021
Ibalizumab (1)
Trogarzo®
Theratechnologies Europe limited
Infectious diseases
Multidrug-resistant HIV infection
50–110
100%
additional benefit not proven
01.08.2020
21.01.2021
Sofosbuvir (3)
Sovaldi®
Gilead Sciences Ireland UC
Infectious diseases
Chronic hepatitis C, 3 to < 12 years
30–50
100%
Hint for
non-quantifiable additional benefit
01.08.2020
21.01.2021
Ledipasvir / Sofosbuvir (3)
Harvoni®
Gilead Sciences Ireland UC
Infectious diseases
Chronic hepatitis C, 3 to < 12 years
100–170
50%
Hint for
non-quantifiable additional benefit
01.04.2020
01.10.2020
Cobicistat (2)
Tybost®
Gilead Sciences GmbH
Infectious diseases
HIV infection, combination with atazanavir or darunavir, 12 to < 18 years
130
100%
additional benefit not proven
15.03.2020
03.09.2020
Fidaxomicin (2)
Dificlir®
Astellas Pharma GmbH
Infectious diseases
Clostridioides difficile infection, children and adolescents
350
54%
Hint for
considerable additional benefit
15.02.2020
20.08.2020
Bedaquilin (3)
Sirturo®
Janssen-Cilag GmbH
Infectious diseases
Multidrug-resistant pulmonary tuberculosis, 12 to < 18 years
9–13
100%
Hint for
non-quantifiable additional benefit
Orphan
01.08.2019
06.02.2020
Dolutegravir / Lamivudin (1)
Dovato®
ViiV Healthcare GmbH
Infectious diseases
HIV infection, ≥ 12 years
52,060–61,380
100%
additional benefit not proven
15.04.2019
17.10.2019
Glecaprevir / Pibrentasvir (2)
Maviret®
AbbVie Deutschland GmbH & Co. KG
Infectious diseases
Chronic hepatitis C, 12 to < 18 years
540
100%
additional benefit not proven
15.01.2019
04.07.2019
Doravirin (1)
Pifeltro®
MSD SHARP & DOHME GMBH
Infectious diseases
HIV infection
57,800–73,700
100%
additional benefit not proven
15.01.2019
04.07.2019
Doravirin / Lamivudin / Tenofovirdisoproxil (1)
Delstrigo®
MSD SHARP & DOHME GMBH
Infectious diseases
HIV infection
48,800–68,000
100%
additional benefit not proven
15.01.2019
04.07.2019
Bedaquilin (2)
Sirturo®
Janssen-Cilag GmbH
Infectious diseases
Multidrug-resistant pulmonary tuberculosis
0
70–100
100%
considerable additional benefit
Orphan
repealed
01.10.2018
22.03.2019
Tenofoviralafenamid (2)
Vemlidy®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis B, ≥ 12 years
12,400–38,100
100%
additional benefit not proven
01.07.2018
20.12.2018
Bictegravir / Emtricitabin / Tenofoviralafenamid (1)
Biktarvy®
Gilead Sciecnes GmbH
Infectious diseases
HIV infection
66,800
100%
additional benefit not proven
15.06.2018
06.12.2018
Dolutegravir / Rilpivirin (1)
Juluca®
ViiV Healthcare GmbH
Infectious diseases
HIV infection
53,000
100%
additional benefit not proven
01.04.2018
20.09.2018
Bezlotoxumab (1)
Zinplava®
MSD Sharp & Dohme GmbH
Infectious diseases
Prevention of recurrent Clostridium difficile infection
6,800–37,600
100%
Indication of
minor additional benefit
15.02.2018
02.08.2018
Letermovir (1)
Prevymis®
MSD SHARP & DOHME GMBH
Infectious diseases
Cytomegalovirus infection
0
1,000–1,800
100%
non-quantifiable additional benefit
Orphan
repealed
15.01.2018
05.07.2018
Elvitegravir / Cobicistat / Emtricitabin / Tenofoviralafenamid (2)
Genvoya®
Gilead Sciences GmbH
Infectious diseases
HIV infection, 6 to < 12 years
100
100%
additional benefit not proven
15.11.2017
03.05.2018
Elvitegravir / Cobicistat / Emtricitabin / Tenofovirdisoproxil (2)
Stribild®
Gilead Sciences GmbH
Infectious diseases
HIV infection, 12 to < 18 years
100
100%
additional benefit not proven
15.10.2017
05.04.2018
Sofosbuvir (2)
Sovaldi®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C, 12 to < 18 years
1,025
100%
Hint for
non-quantifiable additional benefit
01.10.2017
16.03.2018
Darunavir / Cobicistat / Emtricitabin / Tenofoviralafenamid (1)
Symtuza®
Janssen-Cilag GmbH
Infectious diseases
HIV infection
62,050
100%
additional benefit not proven
15.08.2017
15.02.2018
Sofosbuvir / Velpatasvir / Voxilaprevir (1)
Vosevi®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C
104,600
100%
additional benefit not proven
15.08.2017
15.02.2018
Ledipasvir / Sofosbuvir (2)
Harvoni®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C, 12 to < 18 years
5,300
50%
Hint for
non-quantifiable additional benefit
01.08.2017
01.02.2018
Glecaprevir / Pibrentasvir (1)
Maviret®
AbbVie Deutschland GmbH & Co. KG
Infectious diseases
Chronic hepatitis C
104,600
100%
additional benefit not proven
01.04.2017
21.09.2017
Tenofoviralafenamid (1)
Vemlidy®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis B, ≥ 12 years
0
12,400–38,100
100%
additional benefit not proven
repealed
01.04.2017
21.09.2017
Dolutegravir (2)
Tivicay®
ViiV Healthcare GmbH
Infectious diseases
HIV infection, 6 to < 12 years
110
100%
additional benefit not proven
15.12.2016
15.06.2017
Elbasvir / Grazoprevir (1)
Zepatier®
MSD Sharp & Dohme GmbH
Infectious diseases
Chronic hepatitis C
64,800
100%
additional benefit not proven
15.07.2016
05.01.2017
Emtricitabin / Rilpivirin / Tenofoviralafenamid (1)
Odefsey®
Gilead Sciences GmbH
Infectious diseases
HIV infection
56,800–59,300
100%
additional benefit not proven
15.07.2016
05.01.2017
Sofosbuvir / Velpatasvir (1)
Epclusa®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C
100,000
28%
Hint for
considerable additional benefit
15.05.2016
03.11.2016
Emtricitabin / Tenofoviralafenamid (1)
Descovy®
Gilead Sciences GmbH
Infectious diseases
HIV infection
63,000
100%
additional benefit not proven
01.01.2016
16.06.2016
Rilpivirin (2)
Edurant®
Janssen-Cilag GmbH
Infectious diseases
HIV infection, 12 to < 18 years
10
100%
additional benefit not proven
01.01.2016
16.06.2016
Elvitegravir / Cobicistat / Emtricitabin / Tenofoviralafenamid (1)
Genvoya®
Gilead Sciences GmbH
Infectious diseases
HIV infection
56,800
100%
additional benefit not proven
15.11.2015
04.05.2016
Isavuconazol (1)
Cresemba®
Basilea Pharmaceutica International Ltd.
Infectious diseases
Aspergillosis, mucormycosis
1,293–5,342
100%
non-quantifiable additional benefit
Orphan
01.02.2015
16.07.2015
Ombitasvir / Paritaprevir / Ritonavir (1)
Viekirax®
AbbVie Deutschland GmbH & Co. KG
Infectious diseases
Chronic hepatitis C
54,800
9%
Indication of
considerable additional benefit
01.02.2015
16.07.2015
Dasabuvir (1)
Exviera®
AbbVie Deutschland GmbH & Co. KG
Infectious diseases
Chronic hepatitis C
61,700
24%
Indication of
considerable additional benefit
01.12.2014
21.05.2015
Ledipasvir / Sofosbuvir (1)
Harvoni®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C
74,100
79%
Hint for
considerable additional benefit
01.10.2014
19.03.2015
Dolutegravir / Abacavir / Lamivudin (1)
Triumeq®
ViiV Healthcare GmbH
Infectious diseases
HIV infection, ≥ 12 years
54,398
9%
Indication of
considerable additional benefit
01.09.2014
19.02.2015
Daclatasvir (1)
Daklinza®
Bristol-Myers Squibb GmbH & Co. KGaA
Infectious diseases
Chronic hepatitis C
70,500
1.4%
Hint for
considerable additional benefit
01.06.2014
20.11.2014
Simeprevir (1)
Olysio®
Janssen-Cilag GmbH
Infectious diseases
Chronic hepatitis C
64,800
91%
Indication of
considerable additional benefit
01.04.2014
18.09.2014
Cobicistat (1)
Tybost®
Gilead Sciences GmbH
Infectious diseases
HIV infection
57,400
100%
additional benefit not proven
15.02.2014
07.08.2014
Dolutegravir (1)
Tivicay®
ViiV Healthcare GmbH
Infectious diseases
HIV infection, ≥ 12 years
57,399
11%
Proof of
considerable additional benefit
01.02.2014
17.07.2014
Sofosbuvir (1)
Sovaldi®
Gilead Sciences GmbH
Infectious diseases
Chronic hepatitis C
99,841
4%
Indication of
considerable additional benefit
01.01.2014
19.06.2014
Emtricitabin / Rilpivirin / Tenofovirdisoproxil (2)
Eviplera®
Gilead Sciences GmbH
Infectious diseases
HIV infection
46,000
100%
additional benefit not proven
15.06.2013
05.12.2013
Elvitegravir / Cobicistat / Emtricitabin / Tenofovirdisoproxil (1)
Stribild®
Gilead Sciences GmbH
Infectious diseases
HIV infection
49,800
100%
additional benefit not proven
15.01.2013
04.07.2013
Fidaxomicin (1)
Dificlir®
Astellas Pharma GmbH
Infectious diseases
Clostridium difficile infections
33,300
41%
Proof of
considerable additional benefit
15.01.2012
05.07.2012
Emtricitabin / Rilpivirin / Tenofovirdisoproxil (1)
Eviplera®
Gilead Sciences GmbH
Infectious diseases
HIV infection, non-pretreated patients
1,260
100%
Proof of
minor additional benefit
15.01.2012
05.07.2012
Rilpivirin (1)
Edurant®
Janssen-Cilag GmbH
Infectious diseases
HIV infection
1,260
100%
Proof of
minor additional benefit
15.10.2011
29.03.2012
Telaprevir (1)
Incivo®
Janssen Cilag GmbH
Infectious diseases
Chronic hepatitis C
46,000
100%
Indication of
non-quantifiable additional benefit
01.09.2011
01.03.2012
Boceprevir (1)
Victrelis®
MSD SHARP & DOHME GmbH
Infectious diseases
Chronic hepatitis C
46,000
100%
Indication of
non-quantifiable additional benefit