Eye diseases


The category eye diseases as defined by the German Federal Joint Committee (G-BA) groups together medicinal products for the treatment of diseases such as macular degeneration, and for the reduction of intraocular pressure, postoperative pain after eye operations, inflammation after cataract operations or vitreomacular traction. So far XX different medicinal products have been assessed in XX procedures. A major additional benefit has been demonstrated for xx% of the subpopulations (weighted according to patient share in the resolution). A considerable additional benefit has been found for XX% of these subpopulations and a minor additional benefit for XX%. A non-quantifiable additional benefit has been demonstrated for XX% of the subpopulations.

By contrast, the G-BA has stated that an additional benefit compared to the appropriate comparative treatment has not been proved for XX% of the weighted subpopulations, corresponding to xx% of the theoretical total population of xx million patients for all medicinal products evaluated in this therapeutic area.

All G-BA resolutions concerning eye diseases

Bevacizumab (1) Lytenava® Outlook Therapeutics Limited Eye diseases Neovascular age-related macular degeneration 85,500–504,400 100% additional benefit not proven
Polihexanid (1) Akantior® SIFI S.p.A. Eye diseases Acanthamoebic keratitis; ≥ 12 years of age 70–410 100% Hint for non-quantifiable additional benefit Orphan
Faricimab (3) Vabysmo® Roche Pharma AG Eye diseases Macular oedema due to retinal vein occlusion 59,200–96,400 100% additional benefit not proven
Brolucizumab (3) Beovu® Novartis Pharma GmbH Eye diseases Neovascular age-related macular degeneration 85,200–681,400 100% additional benefit not proven
Latanoprost / Netarsudil (1) Roclanda® Santen GmbH Eye diseases Reduction of increased intraocular pressure in open-angle glaucoma or ocular hypertension 87,800 100% additional benefit not proven
Faricimab (2) Vabysmo® Roche Pharma AG Eye diseases Neovascular age-related macular degeneration (AMD) 85,200–681,400 100% additional benefit not proven
Faricimab (1) Vabysmo® Roche Pharma AG Eye diseases Diabetic macular edema (DME) 190,000–241,000 100% additional benefit not proven
Brolucizumab (2) Beovu® Novartis Pharma GmbH Eye diseases Diabetic macular edema 190,000–241,000 100% additional benefit not proven
Voretigen Neparvovec (2) Luxturna® Novartis Pharma GmbH Eye diseases Hereditary retinal dystrophy 100–530 100% Hint for considerable additional benefit Orphan
Idebenon (2) Raxone® Chiesi GmbH Eye diseases Leber's hereditary optic neuropathy (LHOP) 1,400–3,000 100% Hint for non-quantifiable additional benefit Orphan
Levofloxacin / Dexamethason (1) Ducressa® Santen GmbH Eye diseases Infections and inflammations associated with cataract surgery 454,000–811,000 100% additional benefit not proven
Brolucizumab (1) Beovu® Novartis Pharma GmbH Eye diseases Neovascular age-related macular degeneration 0
85,200–681,400
100% additional benefit not proven repealed
Voretigen Neparvovec (1) Luxturna® Novartis Pharma GmbH Eye diseases Hereditary retinal dystrophy 0
100–530
100% Hint for considerable additional benefit Orphan repealed
Ocriplasmin (2) Jetrea® Oxurion NV Eye diseases Vitreomacular traction (VMT) 1,160–16,500 94% Hint for minor additional benefit
Cenegermin (1) Oxervate® Dompé farmaceutici S.p.A Eye diseases Keratitis 1,730–3,170 100% non-quantifiable additional benefit Orphan
Aflibercept (5) Eylea® Bayer Vital GmbH Eye diseases Myopic choroidal neovascularisation 27,500–80,000 100% additional benefit not proven
Idebenon (1) Raxone® Santhera Pharmaceuticals Eye diseases Leber hereditary optic neuropathy 0
1,500–3,000
100% non-quantifiable additional benefit Orphan repealed
Aflibercept (4) Eylea® Bayer Vital GmbH Eye diseases Macular edema following retinal branch vein occlusion 23,100–60,000 100% additional benefit not proven
Tafluprost / Timolol (1) Taptiqom® Santen GmbH Eye diseases Reduction of intraocular pressure in patients with glaucoma/hypertension 95,600 100% additional benefit not proven
Aflibercept (3) Eylea® Bayer Vital GmbH Eye diseases Diabetic macular edema 128,350–132,360 100% additional benefit not proven
Aflibercept (2) Eylea® Bayer Vital GmbH Eye diseases Macular edema following retinal vein occlusion 19,600–21,200 100% additional benefit not proven
Nepafenac (1) Nevanac® Alcon Pharma GmbH Eye diseases Postoperative pain after eye surgery 850,000–1,000,000 100% additional benefit not proven
Ocriplasmin (1) Jetrea® ThromboGenics NV / Alcon Pharma GmbH Eye diseases Vitreomacular traction (VMT) 0
9,970–39,300
95% Hint for considerable additional benefit repealed
Aflibercept (1) Eylea® Bayer Vital GmbH Eye diseases Neovascular age-related macular degeneration 305,000 100% additional benefit not proven
Bromfenac (1) Yellox® Bausch & Lomb/Dr. Mann Pharma Eye diseases Postoperative inflammation of the eye 850,000–1,000,000 100% additional benefit not proven