Saxagliptin / Metformin (4) – Komboglyze®
Diabetes mellitus type 2, combination therapy other than insulin and sulphonylurea
Characteristics
| Start date | 01.08.2017 – Marketing authorisation: 26.06.2017 |
|---|---|
| Resolution | 01.02.2018 |
| INN | Saxagliptin/Metformin |
| Brand name | Komboglyze® |
| Pharm. company | AstraZeneca GmbH |
| G-BA Procedure ID | D-306 |
| ATC code | A10BD10 Combinations of oral blood glucose lowering drugs (A10BD) |
| DDD | 2 U O |
| Therapeutic area | Metabolic diseases |
| Reason for procedure | New therapeutic indication |
| Specialty | ACT change |
Studies and Results
- Clinical trials
- The G-BA commissioned the IQWiG to assess the dossier.
Patients whose blood glucose levels are not adequately controlled by treatment with at least two blood glucose-lowering medicinal products (excluding insulin and sulphonylureas), in addition to diet and exercise
- An additional benefit is not proven.
- The pharmaceutical manufacturer has not provided any data for the assessment of the additional benefit of saxagliptin/metformin in combination with other medicinal products for the treatment of diabetes (excluding insulin and sulphonylureas) compared with the appropriate comparator therapy.
Courtesy translation only, please refer to the German original.
Associated procedures
| Saxagliptin / Metformin (4) | Komboglyze® | AstraZeneca GmbH | Diabetes mellitus type 2, combination therapy other than insulin and sulphonylurea | 77,400 | 100% additional benefit not proven | |
| Saxagliptin / Metformin (3) | Komboglyze® | AstraZeneca GmbH | Diabetes mellitus type 2, monotherapy or combination with insulin | 729,650–748,450 | 100% additional benefit not proven | |
| Saxagliptin / Metformin (2) | Komboglyze® | Bristol-Myers Squibb GmbH & Co. KGaA/ AstraZeneca GmbH | Diabetes mellitus type 2, combination with sulphonylurea | 62,400 | 100% additional benefit not proven | |
| Saxagliptin / Metformin (1) | Komboglyze® | Astra Zeneca GmbH & Bristol-Myers Squibb GmbH CO. KG | Diabetes mellitus type 2 |
0
729,650–748,450 |
85% Hint for minor additional benefit repealed |
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