Mental illnesses

Mental illnesses represent a small group in comparison to other therapeutic areas. Up until this time, xx medicinal products have been assessed in xx resolutions on illnesses such as schizophrenia, depression or ADHD. Of the subpopulations, xx% have seen a major additional benefit, XX% a considerable, XX% a minor and XX% a non-quantifiable additional benefit. The G-BA could see no additional benefit for XX% of the subpopulations weighted according to their share of patients in the respective resolution, corresponding to xx% of the maximum number of xx million patients treatable with these medicinal products.

All G-BA resolutions concerning mental illnesses

Daridorexant (2, reassessment) Quviviq® Idorsia Pharmaceuticals Germany GmbH Mental illnesses Sleep disorders 8,300–218,500 100% no additional benefit
Esketamin (3, reassessment) Spravato® Janssen-Cilag GmbH Mental illnesses Depression, therapy resistent, in combination with SSRI or SNRI 317,000–505,000 100% Hint for considerable additional benefit
Daridorexant Quviviq® Idorsia Pharmaceuticals Germany GmbH Mental illnesses Sleep disorders (mental illnesses) 0
1,900–79,000
100% no additional benefit
Esketamin (2) Spravato® Janssen-Cilag GmbH Mental illnesses Depression, therapy resistant, combination with SSRI or SNRI 0
932,000–974,000
100% no additional benefit
Esketamin Spravato® Janssen-Cilag GmbH Mental illnesses Depression, acute treatment, combination therapy 49,100–69,200 100% Hint for minor additional benefit
Lisdexamfetamindimesilat (2, Elvanse Adult®) Elvanse Adult® Shire Deutschland GmbH Mental illnesses Attention deficit hyperactivity disorder (ADHD), ≥ 18 years 73,000 100% no additional benefit
Cariprazin Reagila® Recordati Pharma GmbH Mental illnesses Schizophrenia 224,000–299,000 21% Indication of minor additional benefit
Vortioxetin Brintellix® Lundbeck GmbH Mental illnesses Major depression 3,369,000–3,669,000 100% no additional benefit
Lurasidon Latuda® Takeda Pharma GmbH Mental illnesses Schizophrenia 250,000 100% no additional benefit
Nalmefen Selincro® Lundbeck GmbH Mental illnesses Reduction of alcohol consumption in alcohol dependence 220,000–248,000 100% no additional benefit
Lisdexamfetamindimesilat Elvanse® Shire Deutschland GmbH Mental illnesses Attention deficit hyperactivity disorder (ADHD), ≥ 6 to < 18 29,600–59,600 100% no additional benefit